nano CBD puzzle

Nano CBD; A Real Thing Or A Marketing Gimmick?

What Is Nano CBD?

Apparently, nano CBD is the next big thing in the CBD-sector.

One of the new ideas is that Nano CBD absorbs faster into the bloodstream than regular CBD.

Is this true or just another well-orchestrated ruse intended to make you buy these products?

There’s only one way to find out!

In this article, we will let you know what Nano CBD is and what science has to say regarding this new trend in the CBD industry.

To understand what’s CBD nano, we first need to understand what the term bioavailability means.

What Is Bioavailability?

When looking for the best CBD consumption methods, you must have come across the term bioavailability.

Bioavailability describes the rate and degree to which a substance gets absorbed into your bloodstream.

Yes, the substances you consume are not utilized wholly.

CBD bioavailability is determined by several factors, including the consumption method.

For instance, only about 20% of it will be available for use by the body when you ingest CBD. On the other hand, inhaling CBD, e.g., through vaping, achieves the highest bioavailability of up to 46%.

What if we could increase the bioavailability of CBD? It would mean using far lass CBD for the same effects as most of it would get absorbed into our bloodstream.

The nano CBD manufacturers promise this, but can nanotechnology help increase CBD bioavailability?

Understanding Nanotechnology

Although the word may sound complicated, nanotechnology means reducing the size of something to nanoscopic dimensions.

By the standard definitions, those dimensions should be less than 0.0000001 meters or 100 nanometers.

To make it more transparent, a single CBD molecule is estimated to be 4440 nanometers in diameter. So when you hear CBD companies talk about nanotechnology, they mean shrinking CBD molecules by 4440%.

The idea is that by shrinking CBD to the size of nanoparticles, your body will be able to break and process it more effectively and efficiently.

Why Would Nano CBD Work Better Than Your Normal CBD?

Some companies wrongly market nano CBD as being water-soluble.

CBD is hydrophobic, meaning it can’t mix with water naturally. CBD is also lipophilic, meaning it can dissolve in fats or lipids. Because CBD won’t usually mix with water, its bioavailability is very low.


While Cannabidiol is oily, your digestive system is watery. We already know oil and water can’t combine naturally.

When you ingest CBD (oily in nature), most of its particles stay in droplets until fully broken down through digestion.

There’s also the issue of the first-pass metabolism.

Can nano CBD be the solution?


According to experts, while CBD is hydrophobic, its molecules seem to act differently compared to their original sizes when it’s broken to nanoparticle size.

When CBD molecules are broken down into nanoparticles, they act and look like a dissolved substance. This is the reason why most retailers market nano CBD as water-soluble CBD.

However, this scientifically doesn’t seem right since CBD does not lose its hydrophobic nature. The only difference is that nano CBD is delivered as very tiny particles.

While science can’t yet explain why, researchers believe that when CBD is broken to nanoparticle size, it binds more readily to both water and lipids.

Your body will also find it easy to absorb and breakdown tiny CBD oil drops since the small CBD particles mean a larger surface area for digestive body enzymes and absorptive tissues to act on.

Still, CBD will need further processing before it can get into the bloodstream. This is not the case for ‘true’ water-soluble molecules. The body absorbs it almost immediately.

What Research Has To Say

According to this study, when CBD is broken down into nanoparticles, it’s surrounded by Nanostructured Lipid carriers, which help transform the already lipid-tolerant compound into an entirely lipophilic compound.

Most nano CBD manufacturers cover CBD with a lipophilic coat known as AM251, URB597, and Rimonabant.

This may help make it easier for the body to break and process the compound.

In a study, the bioavailability of Sativex (a mix of CBD and THC) was compared to that of a THC/CBD nanoemulsion. The nanoemulsion exhibited a higher bioavailability.

Is Nano CBD Better Than Regular CBD?

We need more research to ascertain whether nanoparticles are the real deal as far as CBD use goes.

However, the body seems to absorb nano CBD more effectively than regular CBD. This may mean using less CBD for the same results.

Most nano CBD brands often market their products by giving false information or over-promising to sell their products.

When you hear about nanotechnology in CBD, don’t only think of the tiny particles. Remember, the reason CBD nanoparticles are different is that they have a lipophilic barrier coat.

Whether you go for nano or regular CBD, make sure it’s from organic, high-quality hemp extract.

Also, remember that Nano CBD isn’t an ingredient. If your company only lists nano CBD as the ingredient, it means they’re not ready to reveal the extra ingredients or chemicals used to create those tiny CBD oil drops. Run!

In a nutshell, here are some of the reasons why nano CBD may be better:

The one main reason you might want to try emulsified CBD is that when done correctly, nano CBD may increase the amount of Cannabidiol that ends up in your bloodstream.

Here’s how:

  • Penetration Enhancers

Emulsified CBD particles (nano CBD) often contain penetration enhancers such as propylene glycol and ethanol. These ingredients may increase the rate at which CBD moves across mucous membranes.

  • Increased Surface Area for Digestion

The smaller the CBD oil drops, the more surface area CBD has for contact with the body’s absorptive tissues and enzymes.

Any Possible Side Effects?

Nano CBD promises to deliver CBD quicker into your bloodstream, but are there any possible side effects?

There’s no evidence to suggest that tiny CBD particles may be more dangerous than the regular CBD. Still, some researchers have some concerns on whether these nanoparticles can penetrate and accumulate human cells, thereby causing tissue damage and inflammation.

This report also notes that it’s not known if these tiny particles can pass from a pregnant woman into the unborn child through the placenta.

However, experts advise that the concern should be more about the product safety measures and its ingredients, rather than if the product contains nanoparticles.

Is Nano CBD Better Than Normal CBD?- Take Away

CBD is hydrophobic, and this affects its utilization by the watery digestion tract.

Nanotechnology seems to boost the bioavailability of CBD by breaking down its particles into small sizes. This helps boost how fast and the amount of CBD available for absorption into your endocannabinoid system.

Of course, we need more human trials to ascertain the safety of the continued use of nanoparticles, but so far, the results are promising.

While some brands will overpromise, it’s important to note that for now, there’s no added advantage to using nano CBD other than the fact that it may help increase the bioavailability of the compound.

Trend cautiously when trying any CBD products to ensure that you only use quality and safe products.

Use this article for informational purposes only. For medical advice, talk with your doctor.

Leave a Reply

Your email address will not be published. Required fields are marked *